PETS-中风的验证和可行性:患者报告的中风后治疗负担的测量
Martin Taylor-Rowan1, David T Eton2, Hamish J McLeod1
1School of Health and Wellbeing (M.T.-R., H.J.M., J.R., F.S.M., K.I.G., G.C.), University of Glasgow, United Kingdom.
Stroke
|May 29, 2025
概括
一种新的中风特异性测量,PETS-stroke,有效地评估了中风幸存者的治疗负担. 这种经过验证的工具是可行的和可靠的,用于临床试验和患者护理.
科学领域:
- 神经学 神经学
- 医疗保健服务研究 医疗服务研究
- 心理测量 心理测量 心理测量
背景情况:
- 治疗负担会影响患有长期疾病的个体,因此需要对中风试验进行验证的结果测量.
- 患者治疗和自我管理经验 (PETS) v2.0被调整为创建一种特定于中风的测量方法,PETS-stroke.
- 评估PETS中风的心理测量特性对于其在中风研究中的应用至关重要.
研究的目的:
- 将PETS问卷调整并验证为一种特定于中风的测量方法 (PETS-stroke).
- 评估PETS中风测量的心理测量特性,包括有效性,可靠性和可行性.
- 建立PETS-中风作为中风临床试验的可靠结果衡量标准.
主要方法:
- 一项观察性队列研究招募了来自英国10家医院和苏格兰卫生研究登记处的381名中风幸存者.
- 确认因子分析测试了PETS中风因子结构,而融合有效性则使用与其他患者报告的措施的相关性进行评估.
- 使用类内相关系数评估了测试重复测试的可靠性,通过定性反和缺失数据分析确定了可行性.
主要成果:
- 在PETS中风证明了一个9因素结构与良好的内部一致性 (欧米茄值0.729-0.921).
- 中度至强度的因子负载和与其他措施的相关性表明了良好的有效性.
- 该措施表现出良好的测试-重新测试可靠性 (ICC>0.7) 和积极的参与者对可行性的反,可接受的缺失数据率.
结论:
- 脑中风PETS-stroke是一个在心理测量上健全和可行的仪器,用于测量中风幸存者的治疗负担.
- 这种经过验证的措施可以有效地用于中风临床试验和患者管理.
- PETS中风得分显示出基于多病症和社会经济地位的显著差异,突出其对患者因素的敏感性.
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