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敲除PARM1可以通过PRKCH-MAPK信号通路缓解大动脉的化

Haochang Hu1, Xian Zhu2, Jinyong Chen1

  • 1Department of Cardiology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China; State Key Laboratory of Transvascular Implantation Devices, Hangzhou, Zhejiang, China; Heart Regeneration and Repair Key Laboratory of Zhejiang Province, Hangzhou, Zhejiang, China.

JACC. Basic to translational science
|May 29, 2025
PubMed
概括

前列腺雄激素调节的粘素样蛋白1 (PARM1) 在动脉疾病 (CAVD) 中升高. 向PARM1通过抑制膜间歇细胞的骨质分化来抑制膜化.

关键词:
在 MAPK 信号通道中.第1部分 部分1这就是为什么PRKCHCH.大动脉膜化 化骨质性分化的骨质性差异化

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