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嗅觉膜瘤患者的认知,情感和行为功能:系统性审查

Anton Pashkov^1,2,3, Elena Filimonova^4,5,6, Alexandra Poptsova^4,6

¹FSBI "Federal Center of Neurosurgery", Novosibirsk, Russia. antonpashkov03@gmail.com.

Neurosurgical review

|May 29, 2025

概括

嗅觉膜瘤 (OGM) 经常导致认知和行为问题. 虽然手术后可能有一些恢复,但较大的瘤和特定的方法可能会阻碍进展,需要进一步研究.

科学领域:

神经科学是一个神经科学.
神经外科神经外科
精神病学是一个精神病学.

背景情况:

嗅觉膜瘤 (OGM) 与认知,情感和行为缺陷有关.
在转基因患者中,这些症状尚未得到充分了解.
了解这些缺陷对于改善患者治疗结果至关重要.

研究的目的:

系统地审查OGM患者认知,情感和行为缺陷的患病率,性质和术后结果.
为了确定影响神经心理恢复的因素.
为了指导未来的转基因患者治疗策略.

主要方法:

按照PRISMA指南进行了系统审查,搜索了PubMed,谷歌学者和ScienceDirect.
包括报告OGM患者认知,情感或行为症状的研究.
数据提取和偏差风险评估由两位独立审稿人进行.

主要成果:

38项研究符合纳入标准,显示OGM患者中精神症状的高患病率 (14-100%).
常见的缺陷包括记忆和注意力问题,混乱,迷失方向,抑郁,冷漠和行为变化.
迷你精神状态检查 (MMSE) 评分的术后改善表明认知恢复,受瘤大小和手术方法的影响.

结论:

认知,情感和行为缺陷在OGM患者中很常见,但往往被诊断不足.
标准化评估的有限使用和小样本大小需要更严格的研究.
未来的研究应该专注于多中心合作,前性设计和经过验证的工具,以优化转基因生物的患者护理.

关键词:

前部头骨基部瘤前部头骨基部瘤认知认知是一种认知.神经心理学评估神经心理学评估神经外科神经外科嗅觉沟脑膜瘤是一种嗅觉沟脑膜瘤

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