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在患有多发性硬化症的人群中,步态参数和慢性下肢疼痛的比较

Abbas Tabatabaei¹, Tobia Zanotto², Libak Abou³

¹Mobility and Falls lab, Department of Physical Therapy, Rehabilitation Science, and Athletic Training, School of Health Professions, University of Kansas Medical Center, Kansas City, KS, USA; Landon Center on Aging, University of Kansas Medical Center, Kansas City, KS, USA.

Multiple sclerosis and related disorders

|May 29, 2025

概括

患有多发性硬化症 (pwMS) 的人经历慢性下肢疼痛,表现出明显的步态障碍. 这些发现凸显了针对性康复策略的需要,以解决pwMS患者的疼痛和移动性.

科学领域:

神经学神经学
康复科学康复科学康复科学
生物医学工程生物医学工程

背景情况:

走路异常在患有多发性硬化症 (pwMS) 的个体中很普遍.
慢性下肢疼痛 (CPLB) 与pwMS中步行障碍之间的具体关系尚不清楚.
了解这种联系对于制定有效的管理策略至关重要.

研究的目的:

为了研究和比较pwMS中带有和没有CPLB的步态参数.
为了在这个人群中确定与CPLB相关的特定步态变化.

主要方法:

一项涉及40名pwMS (平均年龄54.3岁,82.5%是女性) 的横截面研究.
参与者根据CPLB的存在或不存在被分类为组,使用修订的密歇根身体地图来确定.
空间时空步行参数的评估是使用标准化的8米步行在压力敏感的走道上进行的.

主要成果:

与没有CPLB (n=17) 的PwMS相比,使用CPLB (n=23) 的PwMS的步行速度显著降低,步数更少,步长更短.
患有CPLB的个体也表现出延长单腿支 (SLS) 时间和更高的SLS时间变化.
观察到的步行速度下降超过了临床上重要的最小差异,表明临床相关性.

结论:

该研究发现,与没有疼痛的对应物相比,PwMS与CPLB的明显步态变化.
这些发现强调了CPLB在多发性硬化症中对步态的影响.
未来的研究应该专注于开发针对CPLB的目标康复干预措施,以改善 pwMS 中的步态.

关键词:

年代记年代记年代记年代记步行方式步行方式多发性硬化症是多发性硬化症.疼痛疼痛疼痛疼痛

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