结肠癌在化学疗法与免疫疗法相结合后经历了手术切除:病例报告
Zhibin Ye1, Jingpeng Li2, Yuqin Zang3
1Department of Gastrointestinal Surgery, Hebei General Hospital, Shijiazhuang, PR China.
Medicine
|May 29, 2025
概括
新辅助免疫疗法和化疗改善了无法切除的结肠癌的外科治疗结果. 这种方法实现了完整的病理反应,使得成功的瘤切除.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 胃肠病学 胃肠病学
背景情况:
- 新辅助免疫疗法与化疗相结合,为局部先进的不可切除结肠癌提供了改善的外科转换率.
- 患者关注的重点是治疗疗效,周期数,手术时间和副作用.
研究的目的:
- 评估新辅助免疫疗法和化疗在将无法切除的结肠癌转化为可切除的状态中的有效性.
- 评估经过新辅助治疗后手术切除的可行性和结果.
主要方法:
- 通过结肠镜检查,活检和CT扫描证实了诊断,显示了一个6.5厘米×5.5厘米的瘤侵入了邻近的组织.
- 进行了三轮新辅助疗法 (化疗+免疫疗法).
- 在新辅助治疗证实了手术候选人之后,进行了 laparoscopic 极端右侧半球切除术.
主要成果:
- 新辅助治疗后的CT扫描显示,患者符合手术的标准.
- 进行了成功的腹腔镜彻底右半球切除术.
- 手术后的病理检查显示,没有存活的瘤细胞.
结论:
- 在结肠癌中,经过手术切除后的新辅助化疗免疫疗法可以实现R0切除和病理完整反应.
- 这种综合方法代表了一种复杂但又有前途的结肠癌晚期治疗策略.
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