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Updated: Aug 14, 2026

Expression and Purification of Virus-like Particles for Vaccination
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基托桑和曼诺斯修改的双功能mRNA-LNP疫苗用于强大的全身和粘膜免疫反应

Jing Yi1, Yicheng Lu2, Nan Liu2

  • 1State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China; College of Pharmacy, Yanbian University, Yanji 133002, China.

Journal of controlled release : official journal of the Controlled Release Society
|May 29, 2025
PubMed
概括

这项研究引入了一种新型的双功能mRNA疫苗,该疫苗有效向肺部免疫细胞,克服粘膜壁垒. 开发的疫苗增强了全身和粘膜免疫力,提供了对像SARS-CoV-2这样的呼吸道病原体有希望的保护.

关键词:
基托桑修饰的PEG脂类豁免权是一种豁免权.脂质纳米颗粒的使用方法修改为曼诺的PEG脂类粘膜疫苗 粘膜疫苗 是一种它们是mRNARNA.

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