相关实验视频

Updated: Sep 20, 2025

Slice Patch Clamp Technique for Analyzing Learning-Induced Plasticity
11:56

Slice Patch Clamp Technique for Analyzing Learning-Induced Plasticity

Published on: November 11, 2017

15.7K

通过配对关联刺激诱导的神经可塑性的多巴胺基调节NMDA受体的参与

Marie C Beaupain1,2, Elham Ghanavati1,2, Amba M Frese1,3,4

  • 1Department of Psychology and Neurosciences, Leibniz Research Centre for Working Environment and Human Factors (IfADo), Dortmund, Germany.

The international journal of neuropsychopharmacology
|May 29, 2025
PubMed
概括

最佳的N-甲基-D-酸盐 (NMDA) 受体激活对于多巴胺调节的神经可塑性至关重要. 通过降低NMDA受体功能,D2受体活性可能会损害长期的强化效应,特别是对敏感性较低的人.

关键词:
这种NMDA受体是NMDA受体.多巴胺是多巴胺的一种.神经可塑性 神经可塑性配对的关联性刺激.

更多相关视频

Long-term Potentiation of Perforant Pathway-dentate Gyrus Synapse in Freely Behaving Mice11:13

Long-term Potentiation of Perforant Pathway-dentate Gyrus Synapse in Freely Behaving Mice

Published on: November 29, 2013

14.3K
Aversive Associative Learning and Memory Formation by Pairing Two Chemicals in Caenorhabditis elegans07:17

Aversive Associative Learning and Memory Formation by Pairing Two Chemicals in Caenorhabditis elegans

Published on: June 23, 2022

2.6K

相关概念视频

Long-term Potentiation01:25

Long-term Potentiation

Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
Hebbian LTP
LTP can occur when...
2.9K
Role of Neurotransmitters in Memory01:23

Role of Neurotransmitters in Memory

Neurotransmitters are integral to the brain's communication system, enabling neurons to transmit signals across synapses. This chemical exchange underpins various cognitive functions, including memory processes. The role of neurotransmitters in memory is multifaceted, influencing the encoding, consolidation, and retrieval of memories through their action on different neural circuits.
 Glutamate and Synaptic Plasticity
Glutamate, the brain's main excitatory neurotransmitter, is...
1.0K
Drugs Affecting Neurotransmitter Synthesis01:29

Drugs Affecting Neurotransmitter Synthesis

Drugs affecting neurotransmitter synthesis can impact the adrenergic neuron and the synthesis of neurotransmitters. For example, α-methyltyrosine and carbidopa target specific enzymes involved in catecholamine synthesis. α-methyltyrosine inhibits the enzyme tyrosine hydroxylase, which converts tyrosine into dopamine. By blocking this enzyme, α-methyltyrosine reduces dopamine production and other catecholamines. Carbidopa, on the other hand, inhibits the enzyme dopa decarboxylase,...
1.6K
Neuroplasticity01:01

Neuroplasticity

Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
808
Long-term Depression01:03

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over...
2.6K