三维对比增强超声波用于评估微波消光区的形状和大小
Huiyu Yang1, Lin Zhao2, Jianmin Ding2
1Department of Ultrasound, The Third Central Hospital of Tianjin, 83 Jintang Road, Hedong District, Tianjin, China; The Third Central Clinical College of Tianjin Medical University, Tianjin 300170, China; Department of Health Management, Tianjin Hospital, Tianjin, China.
Ultrasound in medicine & biology
|May 29, 2025
概括
三维对比增强超声波 (3D-CEUS) 准确评估微波剥离 (MWA) 区域,显示与CECT有很强的一致性. 临床数据,而不是ex vivo模型,应该优化MWA规划.
科学领域:
- 医疗成像医学成像
- 干预性放射学 干预性放射学
- 在瘤学瘤学.
背景情况:
- 微波除 (MWA) 是肝脏瘤的关键治疗方法.
- 准确评估MWA区域尺寸对于治疗疗效和规划至关重要.
- 在评估废除区域时,成像方法和动物模型之间存在差异.
研究的目的:
- 为了比较三维对比增强超声波 (3D-CEUS) 与对比增强计算机断层扫描 (CECT) 来评估MWA区域的大小和形状.
- 量化人类MWA区域和ex vivo牛肝模型之间的差异.
- 为了优化手术前的规划,用于热除手术.
主要方法:
- 对33名接受肝脏瘤皮MWA治疗的患者的回顾性分析.
- 对于MWA区域参数 (LAD,DS,体积,RI) 的3D-CEUS和CECT的相关性和一致性分析.
- 临床病例和ex vivo牛肝模型之间的切除区域特征的比较.
主要成果:
- 在MWA区域评估中,3D-CEUS和CECT之间存在强烈的相关性 (Pearson/Spearman r > 0.87) 和良好的一致性 (ICC 0.81-0.95).
- 在ex vivo牛肝模型中,除了临床病例外,还显示了显著更大的切除区域 (LAD,DS,RI).
- 两种成像方法都证实了临床和活体数据之间的这些差异.
结论:
- 3D-CEUS对于评估MWA区域形态和尺寸的高度准确.
- 临床3D-CEUS数据,而不是外体模型,对于改善手术前规划系统至关重要.
- 准确的成像评估可以提高热除计划的精度.
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