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Updated: Aug 10, 2026

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations
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A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations

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遗传背景影响了Scavenger受体B类型1缺陷小鼠胚胎对外脑病的易感性

Camila Romero-Muñoz1, Patricia Romo-Toledo1, Gabriela Belledonne2

  • 1Biomedical Research and Innovation Center, Universidad de los Andes, Monseñor Álvaro del Portillo 12455, Santiago, Chile; IMPACT, Center of Interventional Medicine for Precision and Advanced Cellular Therapy, Universidad de los Andes, Monseñor Álvaro del Portillo 12455, Santiago, Chile.

Placenta
|May 29, 2025
PubMed
概括

遗传背景显著影响神经管缺陷 (NTD) 风险在Scavenger受体B类型1 (SR-B1) 缺陷小鼠. 孕产妇补充维生素E有效地减少了跨不同遗传背景的NTD发病率.

关键词:
鼠标遗传背景 鼠标的遗传背景神经管缺陷的神经管缺陷这是一个SR-B1受体.维生素E 维生素E 是一种维生素.

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