用内支气管治疗后肺胸病的危险因素:一个队列研究
Kirstine Hermann Jørgensen1,2, Thomas Decker Christensen2,3, Ingrid Louise Titlestad4
1Department of Respiratory Diseases and Allergy, Aarhus University Hospital, Aarhus, Denmark.
概括
肺胸部 (PTX) 是一种严重的风险,用于治疗COPD的内支气管 (EBV) 治疗. 上叶手术和高肺体积增加PTX风险,导致更长的住院时间和肺炎等并发症.
科学领域:
- 肺部医学 肺部医学
- 干预性肺病学 干预性肺病学
- 胸部外科手术 胸部外科手术
背景情况:
- 肺胸炎 (PTX) 是治疗慢性阻塞性肺病 (COPD) 中严重肺气 (emphysema) 的支气管内膜 (EBV) 的重要并发症.
- 了解风险因素和结果对于患者安全和治疗优化至关重要.
研究的目的:
- 为了比较接受EBV治疗的患者的手术前特征.
- 评估EBV植入后有或没有PTX的COPD患者的30天结果.
主要方法:
- 在丹麦 (2017-2023) 接受EBV治疗的患者进行了回顾性的全国性队列研究.
- 从医疗记录提取的数据.
- 对手术前因素和30天不良事件的分析.
主要成果:
- 在228名患者中,有20.2%患有PTX,平均发病时间为7小时.
- PTX风险在上叶EBV放置时显著增加 (aRR 6.32),并且在高目标叶体积和残留体积时增加.
- PTX患者患有较高的骨质疏松症,肺炎 (RR 4.5),血和ICU入院 (RR 9.89) 的比率.
结论:
- 在上叶的EBV治疗,高目标叶体积和高残留体积是PTX的独立风险因素.
- PTX的发生与长时间住院和肺炎和肺风险增加有关.
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