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Updated: Jun 19, 2026

Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice
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随机控制的人类吸入感染后的早期粘膜反应与减弱的Mycobacterium bovis BCG感染

Julia L Marshall1,2, Iman Satti1, Mirvat Surakhy1

  • 1The Jenner Institute, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, OX3 7DQ, United Kingdom.

Nature communications
|May 29, 2025
PubMed
概括

这项研究使用了空气中BCG的人类挑战模型来了解对结核病的早期免疫反应. 它确定了特定的免疫细胞变化和T细胞激活,为未来的疫苗开发提供了信息.

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