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Updated: Sep 20, 2025

Exploring the Regulation of Lipid Droplet Catabolism through Lipophagy
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人体自启动ULK1C:PI3KC3-C1超复杂体的结构和激活

Minghao Chen1,2,3, Thanh N Nguyen3,4,5,6, Xuefeng Ren1,2,3

  • 1Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA.

Nature structural & molecular biology
|May 29, 2025
PubMed
概括

揭示了Unc-51类激酶复合体 (ULK1C) 结构,显示了其与PI3KC3-C1复合体的组装. 这揭示了通过超复杂的形成启动宏自的机制.

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