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Updated: Sep 20, 2025

Using Mouse Oocytes to Assess Human Gene Function During Meiosis I
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Published on: April 10, 2018

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遗传和功能分析揭示了介质基因中的新突变,这些突变是非阻断性亚子精子症的基础

Ying Liu1,2, Jingping Li1, Lejun Li1

  • 1Department of Reproductive Endocrinology, School of Medicine, Women's Hospital, Zhejiang University, Hangzhou, 310006, People's Republic of China.

Journal of assisted reproduction and genetics
|May 29, 2025
PubMed
概括

研究人员在非阻断性亚精子症患者中发现了介质基因中的新型致病突变,包括第一个同卵性MAEL突变. 这些发现提高了对男性不孕症和精子生成失败的理解.

关键词:
在DMRT1中,DMRT1是DMRT1.马埃尔·梅尔 (MAEL) 是一个在MSH5中,它是MSH5.REC11414 在这个问题上.突变突变是一种突变.非阻塞性阿佐精子症.精子发育失败是因为精子发育失败.整体外基因组测序的测序

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