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含有过渡金属复合物的酸盐的合成,表征和生物潜力

Saddam Hussain^1,2, Mehreen Zafar³, Nauman Ali³

¹Institute of Chemical Sciences, University of Peshawar, Peshawar, 25120, Khyber Pakhtunkhwa, Pakistan. mgisaddam@gmail.com.

Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine

|May 29, 2025

概括

这项研究使用Nitroso-R盐合成了新型过渡金属复合物,显示出显著的抗氧化和抗菌特性. ,铜和复合物显示出生物医学应用的显著潜力.

科学领域:

协调化学协调化学
材料科学材料科学材料科学
生物医学应用生物医学应用

背景情况:

协调复合体在医学,工业和分析方面具有多样化的应用.
过渡金属复合物在药物合成,金属提取和净化中至关重要.
酸-R盐 (NRS) 提供了一个独特的连接体结构,具有酸,酸和硫酸盐组.

研究的目的:

使用Nitroso-R盐合成和表征过渡金属复合物 (Mn,Fe,Co,Ni,Cu,Zn).
调查这些新型金属复合物的联合化学和功能性质.
评估生物潜力,包括去氧化降解抑制,抗氧化和抗菌活性.

主要方法:

使用Nitroso-R盐合成和表征过渡金属复合物.
通过FTIR,CHN,XRD和UV-Vis光谱进行结构分析.
生物查包括去氧化降解抑制,DPPH抗氧化活性测定和抗菌检测.

主要成果:

铜和复合体显示出对铁介导降解的显著潜力.
复合体对活性氧物种 (H2O2,Fe(II)) 产生强烈的抑制作用.
DPPH测定证实了抗氧化潜力,在,铜和复合体中具有显著的活性. 铁,,和复合体对克莱布西拉肺炎和细菌细菌表现出显著的抗菌活性.

结论:

合成的Nitroso-R盐金属复合物具有有前途的抗氧化和抗菌特性.
由于其抗氧化能力,,铜和复合物显示出生物医学应用的潜力.
需要进一步的研究来阐明这些新型复合物的精确作用机制.

关键词:

抗微生物药物抗微生物药物在 DPPH 中, DPPH 是脱氧核糖酶的降解降解酸盐-R盐酸盐-R盐是一种过渡金属复合物过渡金属复合物

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