皮质素[D-Arg2,Lys4] (1-4) 胺通过抑制TRPV1/NR2B介导的神经炎症信号传递减轻烧伤疼痛

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Updated: Jan 18, 2026

Establishing a Mouse Model of a Pure Small Fiber Neuropathy with the Ultrapotent Agonist of Transient Receptor Potential Vanilloid Type 1
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Establishing a Mouse Model of a Pure Small Fiber Neuropathy with the Ultrapotent Agonist of Transient Receptor Potential Vanilloid Type 1

Published on: February 13, 2018

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Ajay Modi1, Ankit Uniyal1, Akhilesh1

  • 1Neuroscience and Pain Research Laboratory, Department of Pharmaceutical Engineering and Technology, Indian Institute of Technology (Banaras Hindu University), Varanasi, 221005, Uttar Pradesh, India.

Molecular neurobiology
|May 29, 2025
PubMed
概括

皮肤色素[D-Arg2,Lys4] (1-4) 胺基 (DALDA),一个外围μ-阿片类受体激动剂,有效地减少了烧伤受伤的老鼠的慢性疼痛行为. 这种新的方法可以缓解疼痛,而不会引起成或中枢神经系统的副作用.

关键词:
烧伤 疼痛 烧伤 疼痛达尔达达达尔达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达达炎症 炎症是一种炎症.周围的MO-R是外围的在 TRP 频道.

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