生对肠道微生物群的组成和功能在一个细菌体-主导性肠型的影响
Jinwoo Kim1,2, Jina Ha1, Seongok Kim1,2
1Department of Food Science and Biotechnology, College of Life Science, Sejong University, Seoul 05006, Republic of Korea.
Journal of microbiology and biotechnology
|May 30, 2025
概括
生补充剂改变了肠道细菌的组成,增加了蛋白质细菌在一个主导的细菌体内型的丰富性. 这项研究探讨了生.
科学领域:
- 微生物学 微生物学
- 营养科学 营养科学
- 胃肠病学 胃肠病学
背景情况:
- 生 (Zingiber officinale) 广泛用于和医疗用途.
- 生中的生物活性化合物具有抗氧化,抗炎和代谢调节性质.
- 生对肠道微生物群的影响尚不清楚.
研究的目的:
- 调查生对肠道微生物群组成和功能的影响.
- 分析生在特定肠型 (细菌类-主导) 的影响.
- 提供对肠道微生物组调节的个性化饮食策略的见解.
主要方法:
- 利用一个体外便化模型来评估生的影响.
- 将参与者分为肠型,以减少个体间的变异性.
- 对肠道微生物群进行了分类学和预测功能通路分析.
主要成果:
- 生治疗没有显著改变微生物α多样性,但诱导了结构变化.
- 观察到细菌群水平上的 Bacteroidota 减少和蛋白质细菌增加.
- 观察到Acinetobacter和Enterobacteriaceae (蛋白质细菌) 的相对丰度增加.
- 丰富的途径包括酸代谢和β-氨酸代谢.
结论:
- 生调节肠道微生物群的组成,有利于蛋白质菌相关的基因.
- 基于肠型的分析为研究饮食干预提供了一个结构化的方法.
- 这些发现可能会为肠道健康的个性化营养策略提供信息.
相关概念视频
Bacterial Flora of the Large Intestine
399
The gut microbiome is formed by a vast and diverse community of bacteria that colonizes our large intestine. These bacteria start residing in the gut from birth and continue diversifying throughout life, influenced by factors such as diet, lifestyle, and stress. The gut bacterial community also includes bacteria from food and those that enter the colon through the anus.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
399
Anatomy of the Intestines
71.6K
Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
71.6K
What is Monogastric Digestion?
70.9K
The human body contains a monogastric digestive system. In a monogastric digestive system, the stomach only contains one chamber in which it digests food. Several other animal species also have monogastric digestive systems, including pigs, horses, dogs, and birds. This chapter, however, focuses on the human digestive system.
70.9K
Irritable Bowel Syndrome I: Introduction
257
Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
257


