在儿科炎症性肠病中的身体健康受损
Saija Kantanen1, Kati Räsänen2, Kaija-Leena Kolho3,4
1Department of Pediatrics, Tampere University Hospital, Tampere, Finland.
儿童炎症性肠病 (PIBD) 患者与健康同龄人相比,心肺呼吸和神经肌肉健康程度较低. 诸如生物药物使用和体重指数等因素会影响这些儿童的身体健康.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 运动生理学 运动生理学
- 炎症性肠道疾病研究研究
背景情况:
- 关于儿科炎性肠病 (PIBD) 身体健康的研究有限.
- 了解PIBD中的身体健康水平对于全面的患者护理至关重要.
研究的目的:
- 为了比较PIBD患者的身体健康与健康对照.
- 分析影响PIBD身体健康的疾病和患者相关因素.
主要方法:
- 对73名PIBD患者和74名年龄/性别匹配的对照进行了横截面研究.
- 评估心肺呼吸能力 (最大工作量,氧气吸收峰值) 和神经肌肉健康.
- 测量身体活动和分析疾病特征.
主要成果:
- 与对照组相比,PIBD患者的心肺呼吸能力 (Wmax/kg,VO2峰值/kg) 显著降低.
- 在多项测试中,PIBD患者的神经肌肉健康也减少了.
- 在多变量分析中,生物药物使用与健康正相关,而更高的BMI与负相关.
结论:
- 与健康儿童相比,PIBD与体能明显降低有关.
- 影响PIBD健康的因素的复杂性需要进一步的纵向研究.
- 未来的研究应该调查身体成分,内脏脂肪和与身体健康有关的疾病控制.
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