通过增材制造制造制造的刺激反应性聚合物植入物的最新进展:一篇评论
Sachin Kothawade1, Sudarshan Singh2,3
1Department of Pharmaceutics, SCSSS's Sitabai Thite College of Pharmacy, Shirur, Pune, Maharashtra, 412210, India.
Current pharmaceutical design
|May 30, 2025
概括
智能聚合物正在通过先进的3D和4D打印来彻底改变医疗植入物. 这些对刺激有反应的材料使得适应性强,功能强的植入物能够用于个性化医疗和非侵入性治疗.
科学领域:
- 生物材料科学 生物材料科学
- 聚合物化学 聚合物化学
- 医疗设备工程 医疗设备工程
背景情况:
- 智能聚合物,或刺激响应的聚合物,在响应温度,pH值,光或磁场等外部触发器时表现出可调节的特性.
- 增材制造,特别是3D和4D打印,为植入物几何和功能提供了前所未有的控制.
- 智能聚合物与3D/4D打印的整合为开发下一代医疗植入物提供了一种新的方法.
研究的目的:
- 审查使用3D和4D打印制造的医疗植入物智能聚合物材料的最新进展.
- 探索这些先进材料的临床影响和潜在应用.
- 确定刺激响应性聚合物植入物的开发和制造方面的挑战和未来前景.
主要方法:
- 对刺激反应性聚合物及其在3D/4D打印医疗植入物中的应用进行了全面的文献综述.
- 分析各种适合智能聚合物加工的3D/4D打印技术.
- 对已开发的植入物材料特性,生物相容性和功能性能进行评估.
主要成果:
- 智能聚合物可以创建具有适应能力的高度可定制和功能性的医疗植入物.
- 3D/4D打印有助于精确制造复杂的植入物结构,并集成刺激响应特征.
- 植入物具有执行先进功能的潜力,包括控制药物输送和改变形状的功能.
结论:
- 智能聚合物和3D/4D打印之间的协同作用对个性化医学和非侵入性治疗策略具有重大前景.
- 克服材料安全,生物相容性和制造精度方面的挑战对于临床翻译至关重要.
- 未来的研究方向包括探索新型刺激响应的聚合物和先进的印刷技术,以提高植入物性能.
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