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Updated: Sep 20, 2025

Flow Cytometry-based Assay for the Monitoring of NK Cell Functions
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Flow Cytometry-based Assay for the Monitoring of NK Cell Functions

Published on: October 30, 2016

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骨质母细胞通过RANK/RANKL在多发性髓瘤中抑制NK细胞杀死功能

Nanhao Meng1,2,3, Xueke Zhu1,2,3, Nannan Xie1,2,3

  • 1Department of Hematology, Tianjin Medical University General Hospital, Tianjin, China.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research
|May 30, 2025
PubMed
概括

多发性骨髓瘤骨质母细胞通过RANK/RANKL通路损害自然杀手 (NK) 细胞的功能. 用denosumab阻断RANKL可增强NK细胞活性,并诱导髓瘤细胞亡,提供一种潜在的治疗策略.

关键词:
多发性骨髓瘤是一种多发性骨髓瘤.排名 / 排名 排名自然杀手细胞是自然杀手细胞.骨质母细胞 (osteoblasts) 是一个骨质细胞.

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