相关实验视频
Updated: Jan 24, 2026

07:16
Thermal Ablation for the Treatment of Abdominal Tumors
Published on: March 7, 2011
35.1K
冷却射频废除用于治疗耐火性切除后神经瘤相关的疼痛:一项前性试点研究
Cole W Cheney1, Kyle Mele2, Richard Kendall3
1Division of Pain Medicine, Mayo Clinic Health Systems, Mankato, Minnesota, USA.
概括
对于神经瘤的射频切除 (RFA) 在治疗截肢后疼痛 (PAP) 中显示出有前途. 这项研究发现内部冷却的RFA (C-RFA) 是可行的,尽管需要进一步的研究来选择患者和优化技术.
科学领域:
- 疼痛管理 疼痛管理
- 干预性放射学 干预性放射学
- 神经学 神经学
背景情况:
- 射频除 (RFA) 是一种潜在的治疗方法,用于耐火性神经瘤相关的截肢后疼痛 (PAP).
- 神经瘤疼痛显著影响患者的生活质量.
研究的目的:
- 评估内部冷却的射频剥离 (C-RFA) 对于治疗神经瘤相关的PAP的可行性.
- 评估C-RFA后的疼痛和功能结果.
主要方法:
- 在高等学术医疗中心进行的前性单臂试点研究.
- 八名患有神经瘤相关的PAP的参与者接受了C-RFA.
- 测量结果包括疼痛 (NRS),活动 (GARS),总体印象 (PGIC) 和药物使用 (MQS-III) 在1,3,6和12个月.
主要成果:
- 在12个月后,50%的参与者是NRS响应者 (≥50%的疼痛减轻).
- 对于GARS,PGIC和MQS-III的响应率有所不同,其中一些患者在12个月内出现改善.
- 在C-RFA程序后没有报告任何并发症.
结论:
- 内部冷却的射频除 (C-RFA) 似乎可用于治疗耐火性神经瘤相关的截肢后疼痛 (PAP).
- 需要进一步的研究来优化患者选择和C-RFA技术.
- 需要进行更大规模的前性研究来证实疗效.
相关概念视频
Heating and Cooling Curves
27.3K
When a substance—isolated from its environment—is subjected to heat changes, corresponding changes in temperature and phase of the substance is observed; this is graphically represented by heating and cooling curves.
For instance, the addition of heat raises the temperature of a solid; the amount of heat absorbed depends on the heat capacity of the solid (q = mcsolidΔT). According to thermochemistry, the relation between the amount of heat absorbed or released by a substance, q, and its...
For instance, the addition of heat raises the temperature of a solid; the amount of heat absorbed depends on the heat capacity of the solid (q = mcsolidΔT). According to thermochemistry, the relation between the amount of heat absorbed or released by a substance, q, and its...
27.3K
Pilot and Numeric Relaying
485
Pilot relaying is a type of differential protection used in power systems. It compares electrical quantities at the terminals of equipment via a communication channel instead of direct relay interconnection. This method is essential for transmission lines where the terminals are far apart, typically up to 80 km for lines with 69 to 115 kV ratings. Four types of communication channels are used for pilot relaying:
485
Pain
1.3K
Pain serves as a critical warning signal that alerts the body to potential or actual harm. When mechanical pressure on the skin is intense, such as from a sharp pinch, the sensation transitions from touch to pain. Similarly, extreme temperatures, like a hot pot handle, convert the sensation of heat into pain. Pain can also result from overstimulation of other senses, such as blinding light, loud noise, or the intense heat from habañero peppers. This ability to sense pain is essential for...
1.3K
NMR Spectrometers: Radiofrequency Pulses and Pulse Sequences
1.7K
A pulse is a short burst of radio waves distributed over a range of frequencies that simultaneously excites all the nuclei in the sample. Upon passing a radio frequency pulse along the x-axis, the nuclei absorb energy corresponding to their Larmor frequencies and achieve resonance. This shifts the net magnetization vector from the z-axis toward the transverse plane. This angle of rotation of the magnetization vector, or the flip angle, is proportional to the duration and intensity of the pulse.
1.7K
Analgesia and Pain Management
1.5K
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
1.5K
Primary Motives: Sleep, Sex, and Pain Avoidance
5.4K
Primary motives such as sleep, sex, and pain avoidance are crucial drivers of behavior in humans and animals. These motives ensure survival, reproductive success, and overall well-being by prompting actions that meet essential bodily needs.
Sleep is a fundamental physiological drive that fosters a state of restfulness crucial for several bodily functions. It facilitates body restoration, the process by which the body repairs, rejuvenates, and maintains itself during sleep, including memory...
Sleep is a fundamental physiological drive that fosters a state of restfulness crucial for several bodily functions. It facilitates body restoration, the process by which the body repairs, rejuvenates, and maintains itself during sleep, including memory...
5.4K

