社会经济差异和诊断时的膀癌阶段:全州的队列分析
Alessio Finocchiaro1,2, Anna Tylecki3,4, Silvia Viganò1,5
1Vattikuti Urology Institute Center for Outcomes Research, Analysis, and Evaluation, Henry Ford Health System, Detroit, MI, United States.
JNCI cancer spectrum
|May 30, 2025
概括
通过区域贫困指数 (ADI) 衡量的社会经济差异与诊断时的晚期膀癌阶段有关. 解决这些差异对于改善患者的治疗结果和膀癌护理至关重要.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 健康差异 在健康上的差异
背景情况:
- 膀癌是全球流行的一种恶性瘤.
- 有限的大规模研究存在于社会经济差异和膀癌在诊断时的阶段.
- 本研究研究了区域贫困指数 (ADI) 作为与膀癌阶段相关的社会经济地位的衡量标准.
研究的目的:
- 检查区域剥夺指数 (ADI) 与诊断时膀癌的阶段之间的关联.
- 为了确定社会经济地位是否影响膀癌的检测阶段.
- 为有针对性的干预提供证据,以减少膀癌的健康差异.
主要方法:
- 来自密歇根州卫生和人类服务部 (2004-2019) 的膀癌患者的回顾性分析.
- 区域贫困指数 (ADI) 根据患者的居住人口普查区组分配,分为四分位数.
- 多变量逻辑回归用于评估ADI对晚期疾病 (肌肉侵入性,结节性或转移性) 的影响.
主要成果:
- 较高的ADI四分位数 (最贫困) 与肌肉侵入性疾病 (≥T2),阳性结节状况 (cN+) 和转移性疾病 (cM+) 的增加率有关.
- 增加10个单位的ADI与T2阶段的几率增加了4%,cn+增加了4%,cM+增加了6%.
- 这项研究包括29,010名膀癌患者,结果根据人口因素进行了调整.
结论:
- 较高的社会经济贫困,如ADI所示,与诊断时的晚期膀癌相显著相关.
- 这些发现凸显了膀癌治疗中的严重健康差异.
- 解决社会经济因素对于改善膀癌的结果和减少差异至关重要.
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