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Updated: Sep 20, 2025

Methyl-binding DNA capture Sequencing for Patient Tissues
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完整的参考基因组和泛基因组通过使用测序和数组数据改善了DNA甲基化的全基因组检测和解释

Zheng Dong1, Joanne Whitehead2, Maggie Fu1

  • 1Centre for Molecular Medicine and Therapeutics, University of British Columbia, 950 West 28th Avenue, Vancouver, BC V5Z 4H4, Canada; BC Children's Hospital Research Institute, University of British Columbia, 950 West 28th Avenue, Vancouver, BC V5Z 4H4, Canada; Genome Science and Technology Graduate Program, University of British Columbia, 100-570 West 7th Avenue, Vancouver, BC V5Z 4S6, Canada.

Cell reports
|May 30, 2025
PubMed
概括

新的T2T-CHM13和人类泛基因组引用通过识别更多的CPG和明确的探针来改善DNA甲基化 (DNAm) 研究. 这增强了全表观基因组关联研究 (EWAS),有助于癌症研究的发现.

关键词:
科普:基因组学 基因组学在EPICv2中,我们可以看到EPICv2.照明的人类甲基化EPIC珠子芯片Illumina Infinium 人类甲基化 珠子 芯片 标注无极甲基化EPIC v.2.0 版本在T2T-CHM13中使用.双硫酸盐序列测序 双硫酸盐序列测序癌症 癌症 癌症 癌症 癌症交叉反应探测器探测器表观遗传学是指表观遗传学.全表观基因组协会研究研究.潘格诺姆 (pangenome) 是一个名字.

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