在哈马丹大都市 (伊朗) 哺乳婴儿中对潜在有毒元素 (PTEs) 的概率风险评估
Vahid Ghasemzadeh-Mohammadi1, Masoumeh Moslemi2, Aliasghar Vahidinia3
1Department of Nutrition and Food Hygiene, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
概括
哈马丹的母乳养婴儿面临潜在有毒元素 (PTEs) 的非致癌风险. (As) 和 (Cd) 构成最高风险,特别是在0-2个月的婴儿中.
科学领域:
- 环境健康 环境健康
- 儿科毒理学 儿科毒理学
- 公共卫生 公共卫生
背景情况:
- 母乳是婴儿的主要营养来源.
- 母乳中的潜在有毒元素 (PTEs) 可能对哺乳婴儿构成健康风险.
- 评估PTE暴露对婴儿健康至关重要,特别是在脆弱人群中.
研究的目的:
- 为了评估潜在有毒元素 (PTEs) 暴露在伊朗哈马丹母乳养婴儿中的风险.
- 为了确定与通过母乳传递的PTE相关的非致癌和致癌风险.
- 为了确定特定的PTE和婴儿年龄组具有高风险水平.
主要方法:
- 使用诱导合等离子体质谱法 (ICP-MS) 来分析来自100名母亲的母乳样本.
- 计算危险系数 (HQ) 和总危险系数 (THQ) 以评估非致癌风险.
- 对致癌风险的评估,特别是对 (Cd) 的评估.
主要成果:
- 所有被评估的婴儿都有来自PTE的非致癌性疾病的风险,0-2个月龄的婴儿的风险更高.
- (As) 对超过5%的婴儿构成非致癌风险.
- (Cd) 是致癌风险关注的最高因素,影响了5%的2至4个月龄的婴儿.
- 铁 (Fe) 摄入量最初很高,可能是由于母亲补充剂,但在4-6个月后显著下降.
结论:
- 在哈马丹,母乳养的婴儿暴露于PTE,需要监测和潜在的干预措施.
- 和是关键的PTE,分别对非致癌和致癌风险引起关注.
- 0至2个月龄的婴儿是特别易受伤害的群体,需要特别注意通过母乳接触PTE.
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