严重的COVID-19感染后30个月的心肺长期影响
Julia H Niebauer1, Iscel Ahmet1, Schedl Sarah1
1Department of Cardiology and Emergency Medicine, Klinik Favoriten, Kundratstraße 3, 1100 Vienna, Austria.
概括
严重的COVID-19幸存者经历了显著的长期心肺复苏,但近一半在30个月后仍然有长期COVID症状. 这凸显了管理COVID后疾病的持续临床挑战.
科学领域:
- 心脏病学 心脏病学
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
背景情况:
- 严重的COVID-19可能导致持续的心肺功能障碍和长期COVID症状.
- 了解这些疾病的长期发展轨迹对于患者管理至关重要.
研究的目的:
- 评估症状和长期心肺功能障碍在严重COVID-19后长达30个月.
主要方法:
- 对200名严重的COVID-19患者进行的前性多中心队列研究.
- 6,18和30个月的随访包括成像 (心声学,MRI,CT),肺功能测试和症状评估.
- 对心肺功能,结构异常和长期COVID发生率的分析.
主要成果:
- 大多数成像异常在30个月内消失;在2名患者中出现轻度持续的左心室功能障碍.
- 在大多数患者中,心周溢血和心周炎/心肌炎的迹象消失了.
- 胸部CT显示小纤维变化在94%的患者在30个月;长期COVID发病率仍然高,为49%.
结论:
- 心肺异常在很大程度上回归,但长期COVID在30个月后的近一半患者中仍然存在.
- 图像检测结果与报告的症状之间存在断层,使长期COVID管理复杂化.
相关概念视频
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
3.5K
Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
3.5K
Cardiomyopathy II: Dilated Cardiomyopathy
480
Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
480
COPD: Pathogenesis and Clinical Features
1.8K
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
1.8K
Chronic Obstructive Pulmonary Disease
2.3K
COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
2.3K
Pulmonary Cycle: Exhalation
3.0K
In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
3.0K
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
4.2K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
Chronic Inflammation
4.2K


