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Updated: May 6, 2026

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在抗NMDAR抗体介导脑炎的复发预防里图西马布的使用:一个多中心队列研究

Nabil Seery1,2, Robb Wesselingh1,2, Paul Beech3,4

  • 1Department of Neuroscience, Monash University, Melbourne, Australia.

Neurology(R) neuroimmunology & neuroinflammation
|May 30, 2025
PubMed
概括

单次服用瑞思西玛的疗程显著降低了抗NMDAR抗体介导脑炎的复发风险. 对于需要重新治疗的患者,六个月后的Rituximab会延迟复发,但这种效果会在12个月后减弱.

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Tumor Necrosis Factor (TNF), a proinflammatory cytokine, contributes significantly to the inflammation seen in Crohn's disease. It exists as soluble TNF and membrane-bound TNF, with actions mediated through TNF receptors (TNFR). TNFR activation leads to the release of proinflammatory cytokines, T-cell activation, collagen production, and leukocyte migration, all contributing to inflammation in Crohn's disease. Anti-TNF monoclonal antibodies, namely infliximab (Remicade), adalimumab...
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