解读对沉积物中酸三生物降解的影响:来自分子生物学和计算化学的见解
Dandan Li1, Xiaoyu Wang1, Chen Xie1
1Nanjing Hydraulic Research Institute, Nanjing 210029, China; Key Laboratory of Taihu Basin Water Resources Management, Ministry of Water Resources, Wuxi 214131, China.
Journal of hazardous materials
|May 30, 2025
概括
(Cd) 显著抑制了沉积物中三酸 (TPhP) 的降解,降低了生物降解效率. 在Firmicutes中的生物标志物显示了重金属应力下TPhP生物修复的潜力.
科学领域:
- 环境科学 环境科学
- 环境化学环境化学
- 微生物学 微生物学
背景情况:
- 三酸 (TPhP) 和重金属在沉积物中共存,造成环境风险.
- (Cd) 对TPhP降解的影响尚不清楚.
研究的目的:
- 研究Cd对沉积物中TPhP降解的影响.
- 了解Cd对TPhP生物降解的影响的机制.
主要方法:
- 用不同度的TPhP和Cd进行沉积物化实验.
- 确定TPhP降解产品和降解途径.
- 转录组分析以评估微生物的代谢反应.
- 微生物社区转移的生物标志物分析.
主要成果:
- 在没有Cd的沉积物中,TPhP生物降解效率超过了90%.
- Cd显著抑制了TPhP降解,在较高度下抑制增加.
- 转录基因分析显示,异生菌代谢受抑制,细胞运动,运输和能量通路受损.
- 固菌生物标志物被丰富并与高TPhP+Cd压力下降解基因相关联.
结论:
- 通过扰乱微生物代谢过程,Cd 抑制了 TPhP 的降解.
- 在Cd压力下,固体可能在TPhP降解中发挥关键作用.
- 这些发现为共同污染的沉积物中的生物修复策略提供了洞察力.
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