术后并发症的性别差异 周围动脉疾病下肢再血管化的周围动脉疾病
Roselyn Terrazos-Moreno1, Annie Vu2, Dana Alameddine3
1Yale School of Medicine, New Haven, CT.
Annals of vascular surgery
|May 30, 2025
概括
为外周动脉疾病 (PAD) 进行下肢再血管化 (LER) 的女性患早期血栓形成的风险更高. 男性出现更多的并发症,而女性年龄较大,影响LER结果.
科学领域:
- 血管外科 血管外科
- 心血管医学 心血管医学
- 健康差异 在健康上的差异
背景情况:
- 对外围动脉疾病 (PAD) 的下肢再血管化 (LER) 结果的性别差异对于改善患者护理至关重要.
- 以前的研究表明,接受内血管LER的女性出血风险增加.
- 这项研究调查了开放和内血管LER的术后并发症,比较男性和女性患者.
研究的目的:
- 为了在为外周动脉疾病 (PAD) 进行下肢再血管化 (LER) 的患者中比较性别之间的周术后并发症.
- 为了确定患者特征和LER结果的性别特异性差异.
主要方法:
- 在2013年至2020年期间,对1987名患者进行了4623次LER手术的回顾性图表审查.
- 对患者人口统计,并发症和术后 (30天) 并发症的分析.
- 男性和女性患者之间的结果对开放和内血管LER的比较.
主要成果:
- 女性年龄较大,更有可能是非洲裔美国人,不太可能使用阿司匹林或他类药物.
- 男人吸烟,糖尿病,功能衰竭和冠状动脉疾病的比例更高.
- 女性的早期血栓形成率显著高 (1.7%对比1%),而男性的伤口感染率更高 (5%对比3.3%).
- 在重大截肢,血液瘤,出血或整体发病率方面没有发现显著差异.
- 在女性中发现死亡率上升的趋势 (1.6%对比1%).
结论:
- 在PAD的LER的呈现和术后结果中存在显著的性别差异.
- 接受LER的女性年龄较大,并存在较少的并发症,但患早期血栓形成的风险更高.
- 男性出现更多的并发病和较高的伤口感染率,女性死亡率更高的趋势.
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