支持炎症的饮食和抑郁和焦虑的风险:基于饮食炎症指数的前性研究
Chunyang Pang1, Huan Yu2, Jiali Xie3
1Department of Rehabilitation Medicine, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, PR China; Department of Neurology, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, PR China.
Journal of affective disorders
|May 30, 2025
概括
通过高饮食炎症指数 (DII) 表示的促炎症饮食与抑郁和焦虑的风险增加有关. 相反,抗炎饮食可能会防止这些心理健康状况.
科学领域:
- 营养精神病学 营养精神病学
- 流行病学 流行病学
- 心理健康研究 心理健康研究
背景情况:
- 饮食成分可以通过促炎和抗炎途径影响情绪.
- 饮食炎症指数 (DII) 量化了饮食的炎症潜力.
研究的目的:
- 调查饮食性炎症 (DII) 与发展焦虑和抑郁症的风险之间的联系.
- 探索抗炎饮食在心理健康预防中的潜力.
主要方法:
- 饮食炎症指数 (DII) 由29种食品计算,使用英国生物银行参与者的24小时饮食回忆.
- 通过ICD代码识别的抑郁和焦虑障碍;使用PHQ-9和GAD-7问卷评估情绪.
- 考克斯的比例危险模型用于分析基线DII和事件抑郁/焦虑障碍之间的关系.
主要成果:
- 在14.1年内,较高的DII得分与抑郁情绪 (OR 1.137),抑郁障碍 (HR 1.063),焦虑情绪 (OR 1.094) 和焦虑障碍 (HR 1.023) 的风险增加有关.
- 在调整了社会人口统计学,生活方式和医疗因素后,这些关联仍然很重要.
- 这项研究包括189,835名参与者,抑郁症和焦虑症的发病率分别为每10万人年257.25和272.10.
结论:
- 具有促炎特征 (较高的DII) 的饮食与未来抑郁和焦虑的更高风险密切相关.
- 通过较低的DII表示的抗炎饮食,显示出作为心理健康的保护策略的承诺.
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