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Updated: Jun 13, 2025

Author Spotlight: Studying the Impact of Maternal Dietary Deficiencies on Long-Term Offspring Health Outcomes
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Author Spotlight: Studying the Impact of Maternal Dietary Deficiencies on Long-Term Offspring Health Outcomes

Published on: June 28, 2024

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产前暴露会通过KDM5调节的对发育大脑自的重编程导致后代的认知功能障碍,这种效应被α-甲酸减弱

Zhongyue Wang1, Hailan Wang2, Xiaoshan Peng3

  • 1Center for Global Health, China International Cooperation Center for Environment and Human Health, The Key Laboratory of Modern Toxicology, Ministry of Education, School of Public Health, Suzhou Institute for Advanced Study of Public Health, Gusu School, Nanjing Medical University, Nanjing 211166, Jiangsu, People's Republic of China; Jiangsu Safety Assessment and Research Center for Drug, Pesticide, and Veterinary Drug, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu, People's Republic of China.

Experimental neurology
|May 30, 2025
PubMed
概括

产前暴露会通过改变基因组修饰和自来损害男性后代的记忆力. 在怀孕期间补充alpha-ketoglutarate (α-KG) 可以逆转这些有害的神经发育影响.

关键词:
认知功能障碍 认知功能障碍氨酸脱甲基酶 5 氨酸脱甲基酶神经元自是神经元的自.产前暴露于的情况.α-基质酸盐的使用情况

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