退伍军人患有病毒性呼吸道感染的二次性肺炎球菌病
Lauren A Powers1, Arthur K Chan1, Bethany A Wattengel1
1Department of Pharmacy, Veterans Affairs Western New York Healthcare System, Buffalo, NY, USA.
概括
流感和RSV增加了继发性Streptococcus pneumoniae感染的风险. 冠状病毒疾病2019 (COVID-19) 在住院患者中没有提高这种风险.
科学领域:
- 传染性疾病 传染性疾病
- 肺部病理学 肺部病理学
- 流行病学 流行病学
背景情况:
- 病毒后的细菌感染,如肺炎链球菌,在流感和RSV之后很常见.
- 关于COVID-19和二次S. pneumoniae感染之间的关联存在有限的数据.
研究的目的:
- 为了调查继流感,RSV和COVID-19之后的二次S. pneumoniae感染的风险.
主要方法:
- 在VA医院住院患者的回顾性分析 (2015年1月至2025年3月).
- 在阳性流感,RSV或COVID-19测试后30天内评估S. pneumoniae感染.
- 包括188,721名患者;8,165人患有S. pneumoniae感染.
主要成果:
- 流感 (OR 2.39) 和RSV (OR 2.50) 与感染S. pneumoniae的可能性更高有关.
- COVID-19显示S.肺炎感染的几率降低 (或0.56).
- 慢性肺炎和吸烟也增加了S. pneumoniae的风险.
结论:
- 流感和RSV增加了继发性S. pneumoniae感染的风险.
- COVID-19似乎没有增加感染后S. pneumoniae的风险.
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