在急性中风中使用ApeRio (REVISAR) 进行远距离大脑血管的再通道化
Franziska Dorn1,2, Jan Borggrefe3, Kai Kallenberg4
1Department of Neuroradiology, University Hospital Bonn, Bonn, Germany franziskadorn@yahoo.de.
Journal of neurointerventional surgery
|May 30, 2025
概括
该APERIO混合装置证明了高安全性和有效性作为一线治疗中等血管封闭 (MeVO) 的中风. 这项研究证实了经过机械血栓切除术的MeVO患者的成功再通道化率.
科学领域:
- 神经学 神经学
- 干预神经病学 干预神经病学
- 医疗器械 医疗器械
背景情况:
- 机械血栓切除术 (MT) 在中等血管封闭 (MeVOs) 方面显示出不同的结果.
- 对专门用于MeVO处理的小型设备进行进一步的研究是有必要的.
- 这项研究评估了APERIO Hybrid作为MeVO中风的主要设备.
研究的目的:
- 评估APERIO混合装置在MeVO患者的一线机械血栓切除术中的有效性和安全性.
- 为了确定使用APERIO Hybrid的MT后的再通道化率和临床结果.
- 评估与APERIO混合装置相关的安全性,包括症状性内出血 (ICH).
主要方法:
- 一项前性多中心注册研究包括了134名MeVO患者,他们接受了APERIO或APERIO混合.
- 主要终点是成功的再通道化 (TICI 2b/3) 在三次通过内,没有救援技术或有症状的ICH.
- 结果包括再通道化率,90天后修改的兰金尺度 (mRS) 评分,以及ICH和脑下出血的发生率.
主要成果:
- 主要终点在81.5%的患者 (95% CI 74.5%至88.5%) 中实现.
- 总体上,再通道化成功率 (TICI 2b/3) 为95.8%,在使用APERIO Hybrid.的首次通道化成功率很高.
- 79.0%的患者实现了功能独立 (90天的mRS 0-2),没有报告症状性ICH.
结论:
- 阿佩里奥和阿佩里奥混合设备是安全有效的,作为MeVO中风中MT的第一线治疗方法.
- 在多个中风中心观察到高率的成功再通道化.
- 这些设备代表了管理MeVO中风患者的宝贵选择.
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