在对非可燃尼古丁和烟草制品的随机对照试验中提高了有氧能力
Lucia Spicuzza1,2,3, Francesco Pennisi4,5, Grazia Caci6
1Center of Excellence for the Acceleration of HArm Reduction (CoEHAR), University of Catania, Catania, Italy. lucia.spicuzza@unict.it.
切换到电子烟 (EC) 或加热烟草制品 (HTP) 可以显著提高有氧能力 (V·O2max). 戒烟和减少吸烟都导致心肺呼吸能力大幅增加.
科学领域:
- 心脏呼吸系统的健康状况
- 有氧能力有氧能力.
- 戒烟和减少危害的减少
背景情况:
- 吸烟会对有氧能力产生负面影响,主要是通过降低VO2max.
- 虽然戒烟可以改善健康,但在转换为替代尼古丁产品后,其对VO2max的具体影响尚未得到充分研究.
- 之前没有任何研究评估过电子烟 (EC) 或加热烟草制品 (HTP) 转换后的VO2max变化.
研究的目的:
- 为了前性地研究吸烟行为和有氧能力之间的关系.
- 评估专用EC或HTP使用对V·O2max的特定影响.
- 为了评估不同吸烟表型的V̇O2max变化:持续吸烟者,减少吸烟者和戒烟者.
主要方法:
- 对12周的CEASEFIRE随机对照切换试验的二次分析.
- 根据吸烟行为 (持续,减少,戒烟) 分类的参与者对V̇O2max变化的评估.
- 与基线相比,在独家EC和HTP用户中对V̇O2max的具体评估.
主要成果:
- 戒烟者表现出最大的VO2max改善 (2.7±1.9毫升kg-1分钟-1在第12周).
- 降低剂也表现出显著的VO2max增加 (1.9±1.8毫升kg-1分钟-1在第12周).
- 单独使用EC和HTP导致V̇O2max在第4周和第12周的统计学显著和临床相关改善 (p < 0.0001).
结论:
- 当健康吸烟者转向仅使用EC或HTP时,VO2max的快速改善会发生.
- 这些发现支持戒烟和减少危害策略的心肺呼吸系统益处.
- 在EC和HTP使用者之间没有观察到VO2max改善的显著差异.
更多相关视频
07:10Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease
Published on: August 24, 2019
09:30A Microcontroller Operated Device for the Generation of Liquid Extracts from Conventional Cigarette Smoke and Electronic Cigarette Aerosol
Published on: January 18, 2018
相关概念视频
Drugs Acting on Autonomic Ganglia: Stimulants
Ganglionic stimulants activate NM nicotinic receptors in autonomic ganglia, falling into two categories: nicotine mimetics [e.g., lobeline, dimethylpiperazine, tetramethylammonium] and muscarinic receptor agonists [e.g., muscarine, methacholine]. The first category's action is rapid and blocked by nicotinic receptor antagonists, while the second category's action is delayed and blocked by atropine-like agents. Nicotine, an alkaloid, affects the heart rate by stimulating...
Stimulants
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
COPD: Management Using Bronchodilators and Corticosteroids
Lung Capacity
Pulmonary Function Tests
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
Medical History
