在怀孕32周之前出生的学龄儿童的长期呼吸结果
Amaia Merino-Hernández1, Cristina Ramos-Navarro2, Agustin Muñoz-Cutillas3
1Department of Neonatology, Gregorio Marañón University Hospital, O'Donnell 48 street, 28009, Madrid, Spain. amaia.merino1@gmail.com.
European journal of pediatrics
|May 30, 2025
概括
患有严重支气管肺功能障碍 (BPD) 的儿童面临更高的儿童喘息,喘和住院住院的风险. 轻度BPD (1级) 在这个学龄人群中与没有BPD相比没有增加的呼吸问题.
科学领域:
- 儿科肺病学 儿科肺病学
- 新生儿科学 新生儿科学
- 呼吸系统医学 呼吸系统医学
背景情况:
- 过早出生的婴儿,特别是患有支气管肺功能障碍 (BPD) 的婴儿,在幼儿时期面临呼吸系统风险增加.
- 关于BPD队列中长期呼吸道结果的现有数据通常来自老年人群,可能不反映当前新生儿护理进展.
研究的目的:
- 评估BPD和没有BPD的非常和极度早产婴儿的学龄呼吸系统症状.
- 确定BPD严重程度与学龄人群的长期呼吸道疾病之间的关联.
主要方法:
- 在2012年至2014年期间录取的早产婴儿 (<32周妊娠期) 的前性观察研究.
- 根据NIH的共识标准,BPD的诊断和评分遵循NIH的共识标准.
- 7-10岁时使用全球喘网络 (GAN) 调查问卷评估的呼吸道症状.
主要成果:
- 51%的参与者报告了喘息;在BPD 2-3级 (75%) 和没有BPD/1级 (47%) 中明显更常见.
- 喘症状在BPD 2-3级 (40%) 群体中比没有BPD/1级群体 (12%) 更加普遍.
- BPD 2-3级与前两年 (61%对25%) 的呼吸系统住院病例显著增加有关.
结论:
- 在早产儿中,严重的BPD (2-3级) 与喘,喘症状和早期住院住院率相对较高.
- 在没有BPD的儿童和1级BPD的儿童之间,没有发现呼吸道症状的显著差异.
- 出生时的妊娠年龄 (在28周之前或之后) 在这个队列中没有显著影响呼吸系统症状差异.
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