饮食模式与骨质疏松风险的关联:对观察性研究的元分析
Bing Tan1, HongWei Su2, LanYa Wei3
1Department of Geriatric Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Qingxiu District, No. 6, Shuangyong Road, Nanning, Guangxi Zhuang Autonomous Region, 530000, China.
Journal of orthopaedic surgery and research
|May 30, 2025
概括
高炎症性饮食和不健康的植物性饮食会增加骨质疏松症的风险. 相反,谨慎和健康的饮食模式与骨质疏松症风险降低有关,为预防提供了洞察力.
科学领域:
- 营养科学 营养科学
- 骨健康 骨健康 骨健康
- 流行病学 流行病学
背景情况:
- 饮食模式显著影响骨质疏松症的预防和管理.
- 患有骨质疏松症的患者需要指导来选择有效的饮食策略.
- 这一元分析评估了八种不同的饮食模式,涉及骨质疏松风险.
研究的目的:
- 分析八种饮食模式对骨质疏松风险的影响.
- 为了确定与骨质疏松风险增加或减少相关的饮食模式.
- 为骨质疏松症预防提供基于证据的饮食建议.
主要方法:
- 在2025年4月10日之前对Embase,Web of Science,PubMed和Cochrane图书馆进行系统的文献搜索.
- 使用随机效应模型进行元分析,以比较最低和最高的饮食模式类别.
- 通过亚组分析和使用埃格尔测试的出版偏差来评估异质性;敏感性和修剪和填充分析以缓解偏差.
主要成果:
- 包括20项观察性研究,涉及426,292名参与者.
- 高饮食炎症指数 (DII) 和不健康的植物性饮食指数 (PDI) 分数与骨质疏松症风险增加相关 (ORs > 1).
- 谨慎/健康的饮食模式与骨质疏松症风险降低有关 (OR < 1).
结论:
- 较高的DII和不健康的PDI得分与较高的骨质疏松症风险有关.
- 坚持谨慎/健康的饮食模式表明对骨质疏松症有保护作用.
- 饮食选择在调节骨质疏松症风险方面发挥着至关重要的作用.
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