在儿童和青少年的支气管癌瘤
Claire Brisset1, Marianne Roumy2, Brigitte Lacour3,4
1Unité d'Onco-Hémato-Immunologie pédiatrique, CHU Angers, Angers, France.
Pediatric blood & cancer
|May 31, 2025
概括
儿童支气管癌类瘤 (BCT) 是罕见的,但最常见的儿科肺部瘤. 手术切除是主要的治疗方法,即使有淋巴结的参与,也显示出良好的预后.
科学领域:
- 儿科瘤学 儿科瘤学
- 胸部外科手术 胸部外科手术
- 罕见的癌症 罕见的癌症
背景情况:
- 支气管癌类瘤 (BCT) 是儿童中最常见的肺瘤,尽管总体而言很少见.
- 这些瘤在病理上被分为典型或非典型.
- 完全切除瘤是治疗的确立基石.
研究的目的:
- 描述在法国被诊断患有BCT的儿科患者的临床表现和治疗结果.
- 为了评估手术管理在这个群体中的有效性.
主要方法:
- 使用法国国家癌症登记册进行了一项全国性的回顾性多中心研究.
- 包括在内的是2011年至2022年期间被诊断患有BCT的18岁以下患者.
- 分析了有关诊断,治疗和随访的数据.
主要成果:
- 包括38名儿科患者,平均年龄为15.6岁.
- 典型的癌性瘤占68%的病例,主要是局部化的.
- 所有患者都接受了手术切除,在大多数情况下达到完整的边缘,具有很好的5年生存率 (PFS 87.5%,OS 100%).
结论:
- 儿科BCT通常被诊断为"典型"的癌类瘤.
- 纯粹的手术方法是非常有效的,即使在淋巴结参与 (LN+) 的情况下,预后也非常有利.
- 辅助药物治疗不需要作为一线治疗.
更多相关视频
04:04Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
Published on: February 12, 2017
10.6K
08:34Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
20.5K
相关概念视频
Other Pulmonary Disorders
915
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
915
The Bronchial Tree
3.7K
The human bronchi and bronchial tree play a crucial role in the respiratory system, facilitating the exchange of oxygen and carbon dioxide. Let's delve into the intricate structure and functions of these respiratory components.
The trachea, commonly known as the windpipe, is a tube that connects the larynx (voice box) to the bronchi. At a point called the carina, it bifurcates into two primary bronchi. The right primary bronchus is wider, shorter, and more vertical than the left primary...
The trachea, commonly known as the windpipe, is a tube that connects the larynx (voice box) to the bronchi. At a point called the carina, it bifurcates into two primary bronchi. The right primary bronchus is wider, shorter, and more vertical than the left primary...
3.7K
Barrett Esophagus-II: Clinical Manifestations and Management
321
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
321
COPD: Management Using Bronchodilators and Corticosteroids
331
Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
331
Asthma-IV: Diagnostic and Management
2.6K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
2.6K
Rous Sarcoma Virus (RSV) and Cancer
5.4K
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
5.4K
![Dynamic Imaging of Chimeric Antigen Receptor T Cells with [18F]Tetrafluoroborate Positron Emission Tomography/Computed Tomography](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F62334.jpg&w=3840&q=50)