辩证行为疗法的成本效益与自杀行为自闭症的通常治疗相比:单盲随机对照试验
Anne Huntjens1,2,3, Filip Smit4,5, L M C van den Bosch6
1Department of Clinical Psychology, VU University and Amsterdam Public Mental Health Research Institute, Amsterdam, Netherlands. a.huntjens@vu.nl.
概括
辩证行为疗法 (DBT) 是自闭症成年人经历自杀行为的一种具有成本效益的治疗方法,与通常治疗相比,显著减少了自杀倾向并改善了生活质量.
科学领域:
- 精神病学是一个精神病学.
- 卫生经济学 卫生经济学
- 自闭症谱系障碍研究研究
背景情况:
- 有自杀倾向的自闭症成年人面临着严重的治疗差距.
- 现有的治疗方法往往缺乏针对这一特定人群的基于证据的疗效.
研究的目的:
- 评估辩证行为疗法 (DBT) 与自杀倾向的自闭症成年人通常治疗 (TAU) 的成本效益.
- 评估DBT对质量调整寿命年 (QALYs) 和治疗反应的影响.
主要方法:
- 一个为期12个月的随机对照试验,涉及123名自闭症门诊患者.
- 使用荷兰标准计算医疗保健和社会成本.
- 测量QALY和治疗反应 (通过使用SIDAS减少自杀念头来定义).
主要成果:
- 从医疗保健的角度来看,DBT的成本比TAU低371欧元,获得0.184个QALY,占主导地位的可能性为64%.
- 从社会角度来看,DBT的成本效益比为每获得的QALY 232 欧元.
- 经过敏感性分析的支持,DBT显示治疗响应率优越,自杀念头降低,成本低于TAU.
结论:
- 辩证行为疗法 (DBT) 是一种新的,具有成本效益的,针对自杀倾向的自闭症成年人进行的干预,解决了关键的未满足需求.
- DBT提高了生活质量,减少了自杀念头,支持其更广泛的实施.
- 建议进行进一步的研究,以探索DBT的长期影响和国际可转移性.
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