在澳大利亚卫生系统中青少年异常性关节炎的人口发生率和负担:数据链接研究研究
S J Lain1,2, L Ivancic1,2, J Chaitow3,4
1Child Population and Translational Health Research, Faculty of Medicine and Health, The University of Sydney, Australia.
Journal of paediatrics and child health
|May 31, 2025
概括
患有青少年无形性关节炎 (JIA) 的儿童经常使用医疗服务,在首次JIA入院前后增加了医院和门诊访问. 这凸显了JIA对儿科医疗保健利用率和成本的重大影响.
科学领域:
- 儿科风湿病学 儿科风湿病学
- 医疗保健服务研究 医疗服务研究
- 公共卫生 公共卫生
背景情况:
- 青少年异常性关节炎 (JIA) 是一种慢性疾病,影响儿童.
- 针对儿科JIA的医疗保健利用情况的基于人口的数据有限.
- 了解医疗保健模式对于资源配置和患者管理至关重要.
研究的目的:
- 确定患有JIA的儿童中使用卫生服务的人口发病率.
- 分析医疗保健模式和相关费用在一年前和一年后的第一个JIA入院.
- 量化JIA对医疗保健系统的影响.
主要方法:
- 一项基于人口的数据链接研究在澳大利亚新南威尔士州 (2002-2019) 进行.
- 包括16岁以下的儿童,首次在医院诊断出JIA.
- 链接住院,急诊室 (ED) 和门诊数据集被用于评估医疗服务利用率和成本.
主要成果:
- 1433名儿童首次被诊断为JIA住院;峰值发病率为每年7.2/100,000名儿童.
- 在首次入院前一年,29%的患者被住院治疗,43%的患者访问ED,48%的患者参加了门诊.
- 住院后,44%的患者住院治疗,61%的患者出院诊所治疗,每年每名儿童的费用从4422美元上升至11,806美元.
结论:
- 患有JIA的儿童是医院服务的重要用户.
- 医疗保健的利用,特别是住院和门诊的访问,在第一个JIA入院周围大幅增加.
- 合并动脉炎给受影响的儿童和医疗保健系统带来了相当大的负担.
相关概念视频
Prevalence and Incidence
841
In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
841
Genome-wide Association Studies-GWAS
14.4K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
GWAS does not require the identification of the target gene involved in...
14.4K
The JAK-STAT Signaling Pathway
9.3K
Several cytokine receptors have tightly bound Janus kinase or JAK proteins attached at their cytosolic tail. Small signaling molecules such as cytokines, growth hormones, or prolactins bind to the cytokine receptors and initiate their dimerization. The dimerization brings the cytosolic JAKs together that trans-phosphorylate and activates each other. The activated JAKs now phosphorylate cytosolic tails of the cytokine receptors, which serve as binding sites for adaptor proteins such as SH2...
9.3K
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
71
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
71
Principles of Disease Surveillance
190
Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
190
Rheumatic Heart Disease I: Introduction
53
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
53


