解码酸在调节Fe3+酸微凝输送系统中的酸分子相互作用机制
Hang Liu1, Xi Chen1, Dong Chen1
1College of Food Science, Southwest University, Chongqing 400715, People's Republic of China.
Food chemistry
|May 31, 2025
概括
酸盐微凝中的协同作用显著提高了结构稳定性和营养物质的输送. 这种双重作用的方法改善了叶酸的生物可访问性和高级功能材料的抗氧化活性.
科学领域:
- 材料科学 材料科学 材料科学
- 生物化学 生物化学
- 食品科学 食品科学 食品科学
背景情况:
- 传统的多糖化水凝通常依赖于单金属协调以保持稳定.
- 聚醇,像酸一样,提供多个相互作用点,可以增强水凝的特性.
- 基于酸盐的微凝对受控输送应用有希望.
研究的目的:
- 研究酸结合和Fe3+-酸协调在酸微凝中的协同效应.
- 为了阐明酸调节的酸-Fe3+微凝中的结合机制和相互作用.
- 评估这些双重相互作用对微凝稳定性,受控释放和功能性质的影响.
主要方法:
- 福里埃变换红外光谱 (FTIR) 用于化学键分析.
- 用X射线衍射 (XRD) 来进行结构特征.
- 用于表面元素分析的X射线光电子光谱 (XPS).
- 分子对接模拟用于预测结合相互作用.
主要成果:
- 确定了主要的分子相互作用 (结合和Fe3+-酸协调) 和它们的结合位点.
- 通过双相互作用机制显著加强了酸盐凝网络.
- 叶酸生物可访问性提高了34.1%,封装效率达到97.3%.
- 观察到与86.4%的DPPH基因清除具有协同作用的抗氧化活性.
结论:
- 双重相互作用 (结合和多金属协调) 显著提高了酸盐微凝的稳定性和性能.
- 这种聚醇调制的方法为水凝设计提供了单一协调网络的优质替代方案.
- 为开发具有提高生物可用性和多功能性的先进营养递送系统提供框架.
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