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评估不同婴儿配方奶粉对Streptococcus mutans生物膜形成的影响:一个体外研究

Homa Baninajarian¹, Arezoo Tahmourespour², Amirhossein Vedaei³

¹Dental Research Center, Department of Pediatric Dentistry, Dental Research Institute, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.

The Saudi dental journal

|May 31, 2025

概括

基于牛奶的婴儿配方奶粉显著增加Streptococcus mutans生物膜的形成,而不是基于大豆或化蛋白质配方奶粉. 阿普塔米尔显示出最高的生物膜,而阿普塔米尔HA显示出最低的生物膜,突出了配方类型对幼儿虫风险的影响.

科学领域:

微生物学微生物学
儿科牙科儿科牙科
食品科学食品科学食品科学

背景情况:

幼儿 (ECC) 是一个普遍的全球健康问题.
婴儿配方奶粉在ECC发展中的作用需要进一步研究.
突变性链球菌 (Streptococcus mutans) 是牙腐烂的主要病因.

研究的目的:

评估不同婴儿配方奶粉对Streptococcus mutans生物膜形成的影响.
为了比较牛奶,大豆和化蛋白质配方的效果.
确定可能影响菌致菌生长的特定配方类型.

主要方法:

选择了三种类型的婴儿配方奶粉:牛奶基,大豆基和化蛋白质基.
在含有每个配方的培养介质中评估Streptococcus mutans生物膜的形成.
使用光密度 (OD) 用Cristal Violet染色和ELISA阅读器测量生物膜形成.
统计分析包括独立样本T测试,ANOVA和费舍尔的LSD测试.

主要成果:

在配方类型中观察到Streptococcus mutans生物膜形成的统计学上显著差异 (P < 0.001).
基于牛奶的配方使得生物膜的形成明显大于基于大豆的 (P = 0.003) 和蛋白质化配方 (P < 0.0001).
在基于大豆和蛋白质化剂配方之间,没有发现生物膜形成的显著差异 (P = 0.42).
阿普塔米尔 (牛奶制品) 的平均OD值 (1.81) 是最高,而阿普塔米尔HA (化蛋白) 的平均OD值是最低 (0.61).

结论:

婴儿配方奶粉的成分显著影响Streptococcus mutans生物膜的发展.
基于牛奶的配方促进了比基于大豆和化蛋白质的替代品更大的生物膜形成.
含有水解蛋白质或大豆的配方可能会降低儿童早期菌生长的风险.

关键词:

生物膜是一种生物膜.童年早期的皮肤损伤.婴儿配方奶粉的使用方法突变型链球菌 (Streptococcus mutans) 是一种突变型链球菌.

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