尿路功能障碍在便急症患者中很常见,可能与改变的直肠生物力学有关
Matthew Woo1, Krystyna Pokraka2, Milli Gupta2
1Division of Gastroenterology and Hepatology, Department of Medicine, Cumming School of Medicine, University of Calgary, 1403 29 St NW, Calgary, AB, T2N 2T9, Canada. matt.woo1@ucalgary.ca.
Digestive diseases and sciences
|June 1, 2025
概括
便紧迫性与直肠功能变化和尿路症状增加有关,特别是冲动性尿失禁. 这表明潜在的共同原因需要进一步调查盆底疾病.
科学领域:
- 胃肠病学 胃肠病学
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 盆地底疾病 盆地底疾病
背景情况:
- 便急迫是影响肠道功能障碍和没有肠道功能障碍的患者的一个普遍症状.
- 虽然经常与腹和失禁有关,但便急迫也可能与便秘发生.
- 了解便急症的根本原因对于有效的患者管理至关重要.
研究的目的:
- 为了调查尿路症状在患有便急迫症的患者中的患病率.
- 探索结肠直肠和尿道症状与直肠生理参数之间的关系.
- 识别潜在的共享病理生理机制.
主要方法:
- 包括接受直肠功能测试 (测量力,气球驱逐,气测试) 的患者.
- 症状负担的评估是使用盆地地底痛苦清单 (PFDI),CRAD-8和UDI-6进行的.
- 直肠生理参数与症状严重程度相关.
主要成果:
- 50.7%的患者有便急迫症,经常伴有便失禁 (64.4%) 和急迫性尿失禁 (40.3%).
- 患有便急迫症的患者表现出较低的平均静止,挤压和关节残留压力.
- 在便急迫症患者中观察到更低的直肠膨胀感官值.
结论:
- 在便急迫症患者中,不论是 incontinence,改变的 manometric 和 biomechanical 参数都很明显.
- 便紧迫性与更高的尿路症状负担显著相关,特别是冲动性尿失禁.
- 观察到的相关性表明便和尿路紧迫性之间存在潜在的共享病理生理学,这需要通过直肠和尿动力学测试进行进一步调查.
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