在注射毒品的人群中,性传播感染的流行率和测试覆盖率:系统性审查
Olivia Price1, Paige Webb1, Jason Grebely2
1National Drug and Alcohol Research Centre, UNSW, Sydney, Australia.
Drug and alcohol dependence
|June 1, 2025
概括
注射毒品的人面临性传播感染 (STI) 的高风险. 全球梅毒患病率为3.2%,女性患病率更高,与艾滋病毒有关. 需要更多的研究和综合服务.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 注射毒品 (PWID) 的人因个人和结构因素而经历性传播感染 (STI) 的风险增加.
- 目前关于PWID中STI流行率和检测覆盖率的现有证据有限,需要进行全面的审查.
研究的目的:
- 系统地审查和综合有关全球注射药物使用者中性传播疾病流行率和测试普及率的现有数据.
- 为了确定区域差异和与该人口中STI流行率相关的因素.
主要方法:
- 从2008年1月到2024年4月,搜索了同行评审和灰色文献.
- 采用叙事综合和随机效应元分析,用于区域和全球流行率估计.
- 进行了元回归研究,以探讨性传播感染的流行率和检测覆盖率的异质性来源.
主要成果:
- 数据稀少,将元分析局限于梅毒患病率 (全球估计:3.2%).
- 梅毒患病率因地区而异 (北美地区为0.1%,拉丁美洲为7.2%),女性 (8.1%) 患病率高于男性 (2.3%).
- 较高的艾滋病毒患病率与梅毒率的增加有关;克拉米迪亚 (0-12.5%),淋病 (0-2%) 和性传播疾病检测吸收率 (8-62%) 的数据也被报告.
结论:
- 迫切需要更全面的有关STI流行率和注射毒品的人群中测试普及率的数据.
- 将性传播感染的诊断和治疗纳入血液传播病毒计划是潜在的有效控制策略.
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