相关实验视频
Updated: Sep 19, 2025

07:22
Basophil Activation Test for Allergy Diagnosis
Published on: May 31, 2021
8.5K
慢性自发性疹和慢性诱导性疹
Rina Lee1, Jonathan A Bernstein1
1Department of Internal Medicine, Division of Rheumatology, Allergy and Immunology, University of Cincinnati College of Medicine, Cincinnati, Ohio.
The Journal of allergy and clinical immunology
|June 1, 2025
概括
慢性疹包括持续超过六周的状疹. 本综述涵盖了它的类型,巨细胞在病变发生中的作用,以及为患者福祉提供当前/研究中的治疗方法.
科学领域:
- 皮肤病学 皮肤病学
- 免疫学 免疫学 免疫学
- 过敏学 过敏学
背景情况:
- 慢性疹 (CU) 呈现为的小麦粉,可能伴有血管,持续>6周.
- CU亚型包括慢性自发性疹 (没有触发物) 和慢性诱导性疹 (物理/非物理触发物).
- 乳腺细胞是CU病原体的核心,释放诸如组胺这样的调解剂,导致腹和.
研究的目的:
- 为提供慢性疹病的综合性审查.
- 探索流行病学,病理生理学,亚型,诊断和治疗选择.
- 突出CU对患者生活质量的影响.
主要方法:
- 关于慢性疹的流行病学,病理生理学和临床方面的文献综述.
- 对巨细胞激活通路和媒介释放的分析.
- 检查当前和研究中的治疗目标.
主要成果:
- 慢性疹严重影响患者的日常生活,可通过患者报告的结果来衡量.
- 病理生理学涉及复杂的巨细胞相互作用,受体,细胞因子和信号通路.
- 存在自发和可诱导的CU形式,它们可能会重叠.
结论:
- 了解CU病理生理学对于开发有效疗法至关重要.
- 向乳腺细胞通路为慢性疹提供了治疗潜力.
- 综合管理涉及疾病影响和患者报告的结果.
相关概念视频
Hypersensitivities
1.1K
Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
1.1K
Chronic Bowel Disorders: Introduction
544
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
544
Allergic Reactions
29.0K
Overview
29.0K
Allergic Drug Reactions
1.0K
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
1.0K
Autoimmune Disorders
685
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
Concept and Mechanism of Autoimmune Diseases
The immune...
685
Asthma: Pathogenesis and Management
623
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
623

