在一个医疗中心使用唾液样本对2019年冠状病毒疾病重症患者的阿斯伯吉勒斯菌感染进行观察性研究
Rui-Ming Xu1, Xiao-Li Yuan1, Qing-Qing Ge1
1Department of Emergency, Beijing Tongren Hospital, Capital Medical University, Beijing, China 100176.
类固醇使用的持续时间是重症COVID-19患者中Aspergillus感染的关键风险因素. 虽然这种感染导致了更长的住院时间和更高的成本,但令人惊的是,它与改善的生存率有关.
科学领域:
- 关键护理医学 关键护理医学
- 传染病 传染病 传染病
- 菌类学 菌类学是指菌类学.
背景情况:
- 危急的COVID-19患者面临许多并发症,包括二次感染.
- 在免疫功能低下的人群中,Aspergillus感染构成重大威胁.
研究的目的:
- 在重症COVID-19患者中调查阿斯伯吉路斯菌感染的风险因素,治疗和预后影响.
主要方法:
- 对50名重症COVID-19患者进行了回顾性分析.
- 患者被分为Aspergillus感染组 (10) 和非Aspergillus感染组 (40).
- 风险因素,住院时间,成本和生存结果在各组之间进行了比较.
主要成果:
- 类固醇使用时间是一个重要的风险因素,每增加一天,感染风险增加25.6%.
- 糖尿病史也与阿斯伯吉勒斯菌感染风险相关.
- 患有阿斯伯吉洛菌感染的组体验了更长的住院时间和更高的费用 (p < 0.05).
- 意想不到的是,Aspergillus感染组的生存率更高 (p < 0.05).
结论:
- 长期使用类固醇是这种患者群体中Aspergillus感染的主要危险因素.
- 阿斯珀吉勒斯菌感染与医疗保健利用率增加有关 (停留时间更长,费用更高).
- 尽管资源使用增加了,但阿斯伯菌感染似乎对重症COVID-19患者的生存时间产生了积极的影响.
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