相关实验视频

Updated: Sep 19, 2025

Physiological Characterization of the Coral Holobiont Using a New Micro-Respirometry Tool

Physiological Characterization of the Coral Holobiont Using a New Micro-Respirometry Tool

Published on: April 28, 2023

低氧会扰乱珊瑚和海幼虫的新陈代谢

Benjamin H Glass¹, Katie L Barott¹

¹Department of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA.

The Journal of experimental biology

|June 2, 2025

概括

海洋低氧会通过破坏能量代谢来损害珊瑚和海幼虫. 观察到保存的细胞反应,比如增加糖解,但特定物种的特征影响了结果,突出了制脱氧化的必要性.

科学领域:

海洋生物学海洋生物学
生态生态学生态生态学
代谢学代谢学代谢学

背景情况:

人为污染增加了沿海生态系统中海水缺氧的频率和严重程度.
缺氧对珊瑚和海幼虫生理学产生负面影响,但细胞机制尚不清楚.

研究的目的:

为了研究珊瑚和海幼虫对模拟缺氧的细胞代谢反应.
为了在不同类型的鱼类动物中识别受低氧影响的保存和分离的代谢途径.

主要方法:

Galaxea fascicularis, Porites astreoides 和 Nematostella vectensis 的幼虫被暴露在正常氧和模拟性缺氧 (<2 毫克溶解 O2 L-1 6 小时).
向液体染色体质谱法用于量化代谢物 (氨基酸,甲酸,有机酸,核酸) 的概况.

主要成果:

基线代谢物概况在物种之间有显著差异,表明不同的代谢策略.
缺氧诱导了保存的代谢变化,包括乳酸的增加,这表明糖解,乳酸发酵和脂肪酸β-氧化的上调.
代谢中断与幼虫的游泳行为和生长减少相关.
与藻类共生体的Porites astreoides幼虫对缺氧的代谢反应不那么严重.

结论:

低氧会通过保留和分离的途径扰乱珊瑚和海幼虫的代谢表现.
特定物种的生命史特征,如共生,可以调节对缺氧的反应.
研究结果强调,需要限制海洋脱氧的驱动因素,以保护海洋无脊椎动物.

关键词:

卡尼达尔人卡尼达尔人珊瑚礁中的珊瑚礁河口河口的河口全球变化全球变化氧气过低是因为缺氧.代谢学代谢学代谢学

更多相关视频

Author Spotlight: Advancing Coral Culture - Creating a Semi-Quantitatively Controlled Microenvironment System to Counter Current Limitations

Author Spotlight: Advancing Coral Culture - Creating a Semi-Quantitatively Controlled Microenvironment System to Counter Current Limitations

Published on: July 21, 2023

Author Spotlight: Separation of Coral Host Tissues and Algal Symbionts and Analyzing Their Metabolites

Author Spotlight: Separation of Coral Host Tissues and Algal Symbionts and Analyzing Their Metabolites

Published on: October 13, 2023

相关概念视频

Hypoxia

Hypoxia

Hypoxia is a medical condition characterized by an inadequate oxygen supply to body tissues. It typically manifests as a bluish discoloration of the skin and mucosae, especially in fair-skinned individuals, when hemoglobin (Hb) saturation drops below 75%.
Types of Hypoxia
There are four primary types of hypoxia, each resulting from a different cause:
1. Anemic hypoxia: This type occurs due to insufficient oxygen delivery caused by a lack of red blood cells (RBCs) or RBCs with abnormal or...

Oxygen Transport in the Blood

Oxygen Transport in the Blood

Hemoglobin (Hb) is a crucial molecule in the human body, consisting of four polypeptide chains, each bound to an iron-containing heme group. This unique structure enables hemoglobin to bind to oxygen, with each molecule capable of combining with four molecules of oxygen, leading to rapid and reversible oxygen loading. When fully loaded with oxygen, it is called oxyhemoglobin, while hemoglobin that has released oxygen is called reduced hemoglobin or deoxyhemoglobin. As hemoglobin binds oxygen,...

Oxygen Requirements and Growth Patterns

Oxygen Requirements and Growth Patterns

Microorganisms exhibit diverse oxygen requirements and growth patterns driven by their metabolic strategies and environmental adaptations. Oxygen, while essential for many organisms, can also be toxic under certain conditions, shaping how microorganisms grow and survive.Oxygen Requirements of MicroorganismsMicroorganisms are classified based on their ability to use or tolerate oxygen:● Obligate aerobes like Mycobacterium tuberculosis need oxygen for energy production, as it serves as the...

Adaptive Mechanisms in Cancer Cells

Adaptive Mechanisms in Cancer Cells

Cancer cells accumulate genetic changes at an abnormally rapid rate due to the defects in the DNA repair mechanisms. From an evolutionary perspective, such genetic instability is advantageous for cancer development. Mutant cell lines accumulate a series of beneficial mutations that contribute to their progression into cancer.
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...

Chemical Factors Affecting Respiration Centers

Chemical Factors Affecting Respiration Centers

Chemical factors such as changing CO2, O2, and H+ levels in arterial blood play a critical role in influencing respiration depth and rates. These variations are detected by chemoreceptors—specialized sensors located in two primary body areas. Central chemoreceptors are found throughout the brain stem, including the ventrolateral medulla, while peripheral chemoreceptors are located in the aortic arch and carotid arteries.
CO2 has a potent influence on respiration and is strictly regulated....

Regulation of Angiogenesis and Blood Supply

Regulation of Angiogenesis and Blood Supply

Rapidly dividing tumors, embryos, and wounded tissues require more oxygen than usual, lowering the oxygen concentration in the blood. At low oxygen or hypoxic conditions, an oxygen-sensitive transcription factor called the hypoxia-inducible factor 1 or HIF1 is activated. HIF1 is a dimeric protein of alpha (ɑ) and beta (β) subunits. Under optimal oxygen conditions, HIF1β is present in the nucleus while HIF1ɑ remains in the cytosol. HIF1ɑ is hydroxylated by prolyl...