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Updated: Jun 13, 2026

Evaluation of Polymeric Gene Delivery Nanoparticles by Nanoparticle Tracking Analysis and High-throughput Flow Cytometry
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Published on: March 1, 2013

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聚乙烯胺中的pH依赖性结构变化影响其基因转移效率

Shivalika Sharma1, Manjari Mishra1, Aswin T Srivatsav1

  • 1Department of Chemistry, Indian Institute of Technology Bombay, Powai, Mumbai, 400076, India.

Small (Weinheim an der Bergstrasse, Germany)
|June 2, 2025
PubMed
概括

在基因传递之前,在pH 1.4下对聚乙烯胺 (PEI) 进行调节,可以显著提高转染效率. 然而,暴露于pH3.0会导致PEI自我组装,损害基因传递和细胞吸收.

关键词:
基因转移的转移是基因的转移.散发光的光线散射器对于pH的响应性聚乙烯胺基聚乙烯是什么?自动组装的自动组装机

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