含的对比剂对计算机断层扫描中骨矿物质密度 (BMD) 量化的影响:一项单心回顾性研究,评估阶段,性别和年龄差异
Philip Senti1, Francesco Magoga2, Oriana D'Ecclesiis3
1Faculty of Biomedical Sciences, Università Della Svizzera italiana (USI), Via G. Buffi 13, 6904, Lugano, Switzerland.
La Radiologia medica
|June 2, 2025
概括
对比介质在CT扫描中显著影响骨矿物质密度 (BMD) 测量,在未增强和增强阶段之间观察到显著差异. 这些变化在包括性别和年龄在内的患者人口统计数据中是一致的.
科学领域:
- 放射学和医学成像学 医学成像学
- 骨密度测试 骨密度测试 骨密度测试
- 计算机断层扫描 (CT) 技术
背景情况:
- 准确的骨矿物质密度 (BMD) 评估对于诊断骨质疏松症和管理骨健康至关重要.
- 计算机断层扫描 (CT) 越来越多地用于 BMD 量化,但离子对比介质对这些测量的影响尚未完全理解.
研究的目的:
- 为了评估含的对比剂对从CT扫描中获得的BMD测量的影响.
- 评估对比剂如何影响BMD在不同的收购阶段 (本地,动脉,静脉).
- 根据患者的性别和年龄,调查这些影响的潜在变化.
主要方法:
- 对100名患者的295张CT扫描 (52名男性,48名女性) 进行了回顾性分析,这些扫描是在对比剂给药前后获得的.
- 感兴趣的区域 (ROI) 放置在第一个腰椎上,以记录Hounsfield单位 (HU) 的值.
- 跨本源,动脉和门静脉阶段的BMD值的统计比较,根据性别和年龄进行分层分析 (p < 0.05).
主要成果:
- 在本地,动脉和门静脉阶段 (p < 0.001) 中发现了BMD的显著差异.
- 动脉和静脉阶段的 BMD 与原始阶段有显著差异 (分别为 p = 0.007 和 p < 0.001).
- 男人表现出比女性更高的BMD (p = 0.0007),年轻人比老年人有更高的BMD (p < 0.001),这些群体的相位差异一致.
结论:
- 无增强和增强对比度的CT扫描显示了BMD量化中的显著差异.
- 与原生 (未增强) 阶段相比,静脉阶段表现出特别显著的差异.
- 这些对比诱导的BMD变化在不同患者性别和年龄组中是一致的,这突显了在基于CT的BMD评估中考虑获取阶段的重要性.
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