结核病患者之前的固体瘤病史:在一个结核病发病率低的地区进行多中心回顾性研究
Miguel Borregón1, Paula Rodríguez2, Beatriz Grau2
1Medical Oncology Department, Hospital General Universitario de Elche, Camino de la Almazara, 11, 03202, Alicante, Spain. miguelborregonrivilla@gmail.com.
概括
在一个发病率低的地区,以前的固体瘤和癌症治疗在新的活跃结核病 (TB) 病例中并不常见. 在这种情况下,固体瘤病史不是发展结核病的强烈风险因素.
科学领域:
- 流行病学 流行病学
- 传染性疾病 传染性疾病
- 在瘤学瘤学.
背景情况:
- 结核病 (TB) 的发病率在全球范围内有所不同.
- 了解活跃结核病的风险因素对于公共卫生至关重要.
- 以前的固体瘤和癌症治疗在结核病发展中的作用需要研究,特别是在发病率低的地区.
研究的目的:
- 确定新诊断的活性结核病 (TB) 患者之前固体瘤的患病率和全身癌症治疗.
- 评估活跃结核病与在低结核病发病率地区有固体瘤史之间的关联.
主要方法:
- 在西班牙东南部 (2018-2023) 进行了一项回顾性多中心研究.
- 通过电子健康记录识别了经过培养确认的结核病例.
- 分析了人口统计数据,癌症史和以前的治疗方法.
主要成果:
- 确定了87例活跃的结核病例 (发病率:5.1/100,000人/年).
- 只有4.6%的结核病患者先前有固体瘤病史.
- 在活性结核病和先前的固体瘤,癌症治疗,性别或起源之间没有发现显著的关联.
结论:
- 在这个发病率低的地区,在活跃的结核病患者中很少观察到以前的固体瘤.
- 在这种人群中,固体瘤病史不是发展活跃结核病的重要风险因素.
- 固体癌症患者的常规结核病查在这种情况下没有得到当前证据的支持;建议进行进一步的研究.
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