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汉坦病毒激活Src家族激酶,并通过TLR4/TRAF6通路诱导内皮细胞的超透性

Xiaoyan Wang1, Huanjun Shen1, Hong Du1

  • 1Department of Infectious Diseases, Tangdu Hospital，The Fourth Military University, Xi'an 710038, PR China.

Journal of medical microbiology
|June 2, 2025
PubMed
概括

汉坦病毒 (HTNV) 通过激活托尔类受体4 (TLR4) 来增加血管透性,从而激活TRAF6和Src家族激酶 (SFK). 这一途径酸化粘附结,导致内皮细胞泄漏和综合征的出血性发烧.

关键词:
汉塔安病毒 汉塔安病毒在Src家族的激酶.内皮细胞是内皮细胞.患有综合征的出血性发烧.收费类受体4的收费类受体血管内皮卡德林 (VE-cadherin) 是一种血管内皮卡德林.

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