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在非老年人的皮肤冠状动脉干预

Matti Riihiniemi¹, Jarkko Piuhola^1,2, Matti Niemelä^1,2

¹Research Unit of Biomedicine and Internal Medicine, Medical Research Center Oulu, University of Oulu, Oulu, Finland.

Scandinavian cardiovascular journal : SCJ

|June 2, 2025

概括

穿皮冠状动脉干预 (PCI) 在非老年人中是安全和有效的,特别是对于稳定的冠状动脉疾病. 早期死亡率与ST升高心肌梗塞 (STEMI) 有关,但对部分老年患者来说,整体结果是可以接受的.

科学领域:

心脏病学心脏病学
老年医学老年医学
干预心脏病学干预心脏病学

背景情况:

非老年人 (90岁及以上的患者) 越来越多地接受皮肤冠状动脉干预 (PCI).
在这个特定的老年人群中,PCI的安全性和有效性仍未得到充分研究.
人口老龄化需要了解非常老年人的治疗结果.

研究的目的:

调查接受PCI的非老年人的特征和结果.
评估PCI在不同冠状动脉疾病 (CAD) 病症的非老年人中的安全性和有效性.
确定一年死亡率的初级结果和二次结果,包括出血,心肌梗塞,中风和重复的血管化.

主要方法:

这是一项追溯性研究,对107名非老年人 (平均年龄为91.2岁) 进行了追溯性研究,他们在2012年至2022年期间接受了PCI.
患者被分为三组:ST升高心肌梗塞 (STEMI),非ST升高急性冠状动脉综合征 (NSTEACS) 和稳定的冠状动脉疾病 (CAD).
一年死亡率是主要终点,次要终点包括住院大出血和1年心肌梗塞,中风和重复血管化的发生率.

主要成果:

大多数患者呈现急性冠状动脉综合征 (STEMI:32.7%,NSTEACS:47.7%),而19.6%的患者有稳定的CAD.
与NSTEACS和稳定的CAD组相比,STEMI患者的早期死亡率明显高 (住院:22.9%,30天:34.3%).
一年死亡率在两组之间没有显著差异 (40.0%对27.5%对19.0%),心脏病,中风和重复血管化的1年率分别为7.5%,1.9%和3.7%. 在3.7%的患者中发生了严重的住院出血.

结论:

接受PCI的非老年人的过度死亡率主要与ST升高心肌梗塞 (STEMI) 相关,原因是早期的不良事件.
在这项研究中观察到的死亡率与一般人群相比较,这表明PCI对于精心挑选的非老年人来说是一个可行的选择.
穿皮冠状动脉干预 (PCI) 可以被认为是一个安全和有效的治疗选择的冠状动脉疾病的非老年患者.

关键词:

冠状动脉疾病是一种冠状动脉疾病.这是PCI的PCI.冠状动脉导管治疗的冠状动脉导管不成年人的非成年人.通过皮肤进行冠状动脉干预.

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