神经病变的胃关节疾病可以通过非侵入性身体表面胃映射来诊断:与胃关节测量对比
Christian Sadaka1, Binghong Xu1, Alain J Benitez1,2
1Gastroenterology, Hepatology & Nutrition, The Children's Hospital of Philadelphia, Pennsylvania, USA.
Neurogastroenterology and motility
|June 2, 2025
概括
身体表面胃映射 (BSGM) 可靠地识别胃肠神经病变,与恶心和胀气等症状相关. 这种非侵入性测试表明,当ADM不可行时,它可以作为 antroduodenal manometry (ADM) 的替代方案.
科学领域:
- 胃肠病学 胃肠病学
- 医学诊断 医学诊断 医学诊断
- 儿科健康 儿科健康
背景情况:
- 胃肠膜内测 (ADM) 是诊断上部胃肠 (GI) 运动障碍的黄金标准,但具有侵入性和昂贵性.
- 身体表面胃映射 (BSGM) 提供了一种非侵入性方法来评估胃功能.
- 这项研究旨在评估儿科患者BSGM和ADM之间的相关性.
研究的目的:
- 评估BSGM与ADM相比,在患上上部肠道疾病的儿童中,BSGM的诊断准确性.
- 确定BSGM是否可以可靠地识别胃肠道神经病变和其他运动异常.
- 探索BSGM发现与患者报告的症状之间的相关性.
主要方法:
- 同时的ADM和BSGM在儿科受试者中进行.
- 在ADM中使用了高分辨率的水透导管.
- 一个症状日志应用程序和恶心严重程度尺度 (NSS) 被用来跟踪实时症状.
主要成果:
- 包括15名受试者 (年龄10-19岁),ADM诊断包括神经病变,肌肉病变和正常运动.
- 一种失节的BSGM表型与ADM识别的神经病变有很强的相关性 (p=0.001).
- 在83.3%的病例中,BSGM的发现与正常的ADM一致,并且与恶心和胀气严重程度相关.
结论:
- BSGM是一种可靠的,非侵入性的生物标志物,用于识别儿童的胃肠神经病变.
- BSGM失律现象表与恶心和胀气症状有很强的相关性.
- 当后者不可行时,BSGM为ADM提供了一个可行的替代方案.
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